The U. The FDA remains committed to advancing novel treatment options for areas of unmet patient need, particularly for diseases affecting children. Cystic fibrosis, a rare, progressive, life-threatening disease, results in the formation of thick mucus that builds up in the lungs, digestive tract, and other parts of the body. It leads to severe respiratory and digestive problems as well as other complications such as infections and diabetes. Cystic fibrosis is caused by a defective protein that results from mutations in the CFTR gene. While there are approximately 2, known mutations of the CFTR gene, the most common mutation is the Fdel mutation.
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From Men's Health. Given the new movie Five Feet Apart -which is about two cystic fibrosis patients who meet in a hospital and fall in love played by actors Cole Sprouse and Haley Lu Richardson -you might suddenly be curious what the condition actually is. You might also wonder whether it really is risky for a couple with cystic fibrosis to be around each other. The answer is yes, but not necessarily for the reason you might think. Here's a basic overview of the disease in the movie and how it compares to real life, including why CF patients can't be around each other. Cystis fibrosis CF is a life-threatening, inherited disease that causes progressive damage to organs including the lungs, pancreas, liver, intestines, sinuses, and sex organs.
In cystic fibrosis, the airways fill with thick, sticky mucus, making it difficult to breathe. The thick mucus is also an ideal breeding ground for bacteria and fungi. Cystic fibrosis CF is an inherited disorder that causes severe damage to the lungs, digestive system and other organs in the body. Cystic fibrosis affects the cells that produce mucus, sweat and digestive juices. These secreted fluids are normally thin and slippery.